Plasma Treatment
Molecular Bio-Functionalization
Targeted Localized Implantation
Controlled Kinetic Drug Release
Cold atmospheric plasma functionalization precisely implants reactive oxygen and nitrogen species (RONS) into hydrogel polymer networks.
Our process integrates specific biomolecules, programming the scaffold for targeted cellular interaction and therapeutic response.
Engineered scaffolds are designed for high-precision localized delivery, minimizing systemic exposure and maximizing therapeutic efficacy.
Customizable degradation rates ensure sustained and controlled release kinetics, perfectly matched to tumor histology and treatment protocols.
Quantitative Scientific Metrics
100%
Filling of the resected tumor site for a Personalized medicine
~90%
Healthy cells viability to ensure selectivity
6-fold
Reduction of the chemotherapy dosis
Explore our body of peer-reviewed scientific articles and key presentations delivered at international oncology and cold plasma physics congresses validating PlasmOnCo's plasma-engineered hydrogel technology.
Peer-Reviewed Manuscripts
Key publications from the PlasmaMED Lab Research Group at UPC towards cold atmospheric plasma interaction with the hydrogel scaffolds, localized RONS release dynamics, biological response and microenvironment modulation.
• M. Živanić, A. Espona-Noguera, H. Verswyvel, E. Smits, A. Bogaerts, A. Lin, C. Canal. Injectable Plasma-Treated Alginate Hydrogel for Oxidative Stress Delivery to Induce Immunogenic Cell Death in Osteosarcoma, Adv. Funct. Mater., 34, 2312005 (2024)
• J. Tornin, C. Labay, F. Tampieri, M.P. Ginebra, C. Canal. Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures, Nature Protocols, 16, 2826 (2021)
• C. Labay, M. Roldán, F. Tampieri, A. Stancampiano, P. Escot Bocanegra, M.-P. Ginebra, C. Canal, Enhanced Generation of Reactive Species by Cold Plasma in Gelatin Solutions for Selective Cancer Cell Death, ACS Appl. Mater. Interfaces, 12, 42, 47256 (2020)
Advance Oncology Research
Collaborate with our team to explore the potential of plasma-functionalized hydrogels in your next breakthrough.